Centro Studi GISED

Il progetto è stato sostenuto dal Research Institute for Fragrance Materials e coordinato dal Centro Studi GISED nell’ambito di una collaborazione europea.

E' stato intervistato un campione di 12377 soggetti (53,9% donne, età mediana 43 anni) rappresentativo della popolazione adulta in vari Paesi europei (Italia, Olanda, Germania, Svezia, Portogallo). Di questi, un campione di 3119 soggetti è stato anche testato per allergia a profumi.
L’importanza dello studio si può apprezzare se si considera che sono allo studio a livello europeo norme per il controllo del contenuto dei profumi nei prodotti di impiego comune.

Risultati

I risultati ottenuti finora sono stati oggetto di varie pubblicazioni:

van Amerongen CCA, Ofenloch RF, Cazzaniga S, et al. Skin exposure to scented products used in daily life and fragrance contact allergy in the European general population - The EDEN Fragrance Study. Contact Dermatitis. 2021;84:385-394.

Bruze M, Engfeldt M, Elsner P, et al. Validation of questionnaire algorithm based on repeated open application testing with the constituents of fragrance mix II: The EDEN Fragrance Study. J Eur Acad Dermatol Venereol. 2021;35:1692-1701.

Bruze M, Mowitz M, Ofenloch et al. The significance of batch and patch test method in the establishing of contact allergy to fragrance mix I. EDEN fragrance study group. Contact Dermatitis. 2019;81:104-109.

Ofenloch RF, Schuttelaar ML, Svensson Å, et al. Socioeconomic Status and the Prevalence of Skin and Atopic Diseases in Five European Countries. Acta Derm Venereol. 2019;99:309-314.

Svensson A, Ofenloch RF, Bruze M, et al. Prevalence of skin disease in a population-based sample of adults from five European countries. Br J Dermatol. 2018;178:1111-1118.

Schuttelaar MLA, Ofenloch RF, Bruze M, et al. Prevalence of contact allergy to metals in the European general population with a focus on nickel and piercings: The EDEN Fragrance Study. Contact Dermatitis. 2018;79:1-9.

Diepgen TL, Ofenloch RF, Bruze M, et al. Colophony as marker for fragrance allergy in the general European population. Br J Dermatol. 2016;174:695-6

Diepgen TL, Naldi L, Bruze M, et al. Prevalence of contact allergy to p-phenylenediamine (PPD) in the European general population. J Invest Dermatol. 2016;136:409-15.

Diepgen TL, Ofenloch RF, Bruze M, et al. Prevalence of contact allergy in the general population in different European regions. Br J Dermatol. 2016;174:319-29.

Diepgen TL, Ofenloch RF, Bruze M, et al. Prevalence of fragrance contact allergy in the general population of five European countries – a cross-sectional study. Br J Dermatol 2015;173:1411-9.

Vogel TA, Coenraads PJ, Bijkersma LM, et al. p-Phenylenediamine exposure in real life?-?a case-control study on sensitization rate, mode and elicitation reactions in the northern Netherlands. Contact Dermatitis. 2015;72:355-61.

Naldi L, Cazzaniga S, Gonçalo M, et al. EDEN Fragrance Study Group. Prevalence of self-reported skin complaints and avoidance of common daily life consumer products in selected European Regions. JAMA Dermatol. 2014;150:154-63.

Rossi M, Coenraads PJ, Diepgen T, et al. Design and feasibility of an international study assessing the prevalence of contact allergy to fragrances in the general population: the European Dermato-Epidemiology Network Fragrance Study. Dermatology. 2010;221:267-75

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