What we do
Lichen sclerosus (LS) is an acquired inflammatory disease, with chronic evolution and immune-mediated pathogenesis, often associated with other autoimmune diseases and with the presence of circulating auto-antibodies, both organ and non-organ specific.
The disease is characterized by a distinct predilection for the female adult population with an incidence rate ratio of female/male of about 10:1, with a preferential localization at the level of ano-genital area, in both genders and in all ages of life.
Actually in the medical literature there are no large case studies to define epidemiological and clinical characteristics, and factors involved in the onset of this clinical condition in the Italian population.
Centro Studi GISED, in collaboration with the SIDeMaST group on diseases of the mucous membranes, conducted a clinical-epidemiological study, lasting 24 months, in male and female patients, of any age, suffering from genital LS.
The study used an epidemiological card for collecting anamnestic, physiological and pathological data to assess which are risk factors for the disease, clinical data on LS and previous and/or ongoing treatments.
Collected data (729 subjects) will be analyzed in order to assess the epidemiology of genital LS in various components of the population, to identify any associated diseases and possible risk factors, to deepen knowledge of the symptoms, to assess the incidence of skin cancers, to analyze current therapies and their advisability, etc.
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