Centro Studi GISED

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A tattoo is made by inserting indelible ink into the dermis layer of the skin to decorate the skin surface. More and more people, worldwide, especially young adults and teenagers, decorate their skin by permanent tattoos, many times occupying a large skin surface and using several colors. In Italy, according to ISS data, about 13 people out of 100 have a tattoo on their skin.

Increasing tattooing has led to an increase of possible adverse reactions classifiable into: infections, acute inflammatory reactions, photo-induced reactions, granulomatous, lichenoid and pseudolymphomatous reactions. In addition, the tattoo can be the site of localization of primary skin diseases, e.g. lichen planus, psoriasis, sarcoidosis and lupus erythematosus. Cases of melanomas "hindered" by the tattoos have been also reported. Medical complications after tattooing are often known only by physicians, while the public is generally unaware of adverse effects on health.

To collect reports of tattoo adverse reactions, Centro Studi GISED has started an online spontaneous reporting system of suspected tattoo reactions which allows also to upload clinical images.

REACTOO's collects information, among the others, on the localization of the tattoo, on the pigments used, on the date when the tattoo was made, on the date of the onset of the reaction, and on the reaction appearance and associated symptoms.

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