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PsoMother was a project coordinated by the Department of Epidemiology of the Lazio region, with the aim of studying "The safety of drugs in women with psoriasis exposed to new and old drug treatments: the impact on the health of mother and child".

In particular, different data sources were used (administrative data, registry data, data provided by patients through the project website), to evaluate the impact of sex on psoriasis and its treatments on fertility, pregnancies, breastfeeding (PsoMother project).

In addition to the Lazio DEP, other participants in the project were:

  • Azienda ULSS n. 8 Berica, Vicenza
  • Dipartimento Direzione Medica Ospedaliera, Azienda Ospedaliera Universitaria Integrata Verona
  • Centro Studi GISED

The project has a dedicated website (www.psomother.org), which development was managed by Centro Studi GISED.

A first study, carried out in the Lazio region, took into consideration women who had given birth to a child, with at least one prescription for psoriasis or rheumatoid arthritis in the six months before the last menstruation, which were respectively 525 and 293. The percentage of women with psoriasis who received treatment before pregnancy in this study was similar to that of the patient population in general. Later, as the pregnancy progressed, the rate of prescriptions decreased for all types of treatment, rising after childbirth, although to a lesser extent than in the pre-pregnancy period. It has generally been observed that women with chronic diseases, such as psoriasis and rheumatoid arthritis, discontinue many of their therapies during pregnancy (1).

  1. Belleudi V, Poggi FR, Perna S, et al. Drug discontinuation in pregnant women with psoriasis: The PSO-MOTHER cohort study. Pharmacoepidemiol Drug Saf. 2020;29(8):904-912.

The complete list of publications and the summary of the results of the study are available on the website dedicated to the project.

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