What we do
Stevens-Johnson Syndrome (SJS), Toxic Epidermal Necrolysis (TEN), Acute Generalized Exanthematous Pustulosis (AGEP) and DRESS-Syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) are rare but severe, drug-related adverse reactions, of high morbidity and mortality.
Lombardy, a region with nine million inhabitants and a high rate of computerization, offers an ideal setting to control, characterize, and study the risk factors for the above events.
The React-Lombardia project, promoted by the Lombardy region and coordinated by the Centro Studi GISED in the regional programs area of pharmaco vigilance, arises from the intention of:
The project, so far, involves, 22 hospital centres located in 10 provinces of Lombardy (see map).
All doctors working in Lombardy will be able to collaborate in the project, reporting every new case of cutaneous drug-related reaction to the project web site www.react-lombardia.net.
Data collected during the first five years of the study were published in two scientific articles: